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:: J. Biol. Chem. JBC Papers in Press for 27 Oct 2010 ::

Journal of Biological Chemistry JBC Papers in Press Alert

New Journal of Biological Chemistry JBC Papers in Press articles have been made available
(for the period 26 Oct 2010 to 27 Oct 2010):

Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily
Jeng Yeong Chow, Bo Xue, Kang Hao Lee, Alvin Tung, Long Wu, Robert C. Robinson, and Wen Shan Yew
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.177139

Arginine 104 is a key catalytic residue in leukotriene C4 synthase
Agnes Rinaldo-Matthis, Anders Wetterholm, Daniel Martinez Molina, Johanna Holm, Damian Niegowski, Eva Ohlson, Par Nordlund, Ralf Morgenstern, and Jesper Z. Haeggstrom
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.105940

bacillus subtilis CwlP of the SP-beta prophage has two novel peptidoglycan hydrolase domains, muramidase and cross-linkage digesting D,D-endopeptidase
I. Putu Sudiarta, Tatsuya Fukushima, and Junichi Sekiguchi
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.156273

Gene Regulation
STAT1 is a master regulator of pancreatic beta cells apoptosis and islet inflammation
Fabrice Moore, Najib Naamane, Maikel Luis Colli, Thomas Bouckenooghe, Fernanda Ortis, Esteban N. Gurzov, Mariana Igoillo-Esteve, Chantal Mathieu, Gianluca Bontempi, Thomas Thykjaer, Torben F. Orntoft, and Decio L. Eizirik
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.162131

The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x
Lulzim Shkreta, Laetitia Michelle, Johanne Toutant, Michel L. Tremblay, and Benoit Chabot
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.162644

Engineered external guide sequences effectively block viral gene expression and replication in cultured cells
Xiaohong Jiang, Yong Bai, Paul Rider, Kihoon Kim, Chen-Yu Zhang, Sangwei Lu, and Fenyong Liu
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.158857

Protein Synthesis and Degradation
Biochemical and structural studies of a HECT-like ubiquitin ligase from E. coli O157:H7
David Yin-wei Lin, Jianbo Diao, Daoguo Zhou, and Jue Chen
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.167643

Mechanisms of auto-inhibition of IRF-7 and a probable model for inactivation of IRF-7 by Kaposi's Sarcoma-associated herpesvirus protein ORF45
Narayanan Sathish, Fan Xiu Zhu, Ellis E. Golub, Qiming Liang, and Yan Yuan
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.150920

Decoding toxicity: deducing the sequence requirements of IbsC, a type I toxin in Escherichia coli
Wendy W.K. Mok, Nirav H. Patel, and Yingfu Li
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.149179

Molecular Bases of Disease
Molecular basis of reduced glucosylceramidase activity in the most common gaucher disease mutant N370S
Marc N. Offman, Marcin Krol, Israel Silman, Joel L. Sussman, and Anthony H. Futerman
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.172098

Protein Structure and Folding
X-Ray and Biochemical Analysis of N370S Mutant Human Acid β-glucosidase
Ronnie R. Wei, Heather Hughes, Susan Boucher, Julie J. Bird, Nicholas Guziewicz, Scott M. Van Patten, Clark Qun Pan, and Tim Edmunds
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.150433

TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells
Christian W. Keller, Claudia Fokken, Stuart G. Turville, Anna Lunemann, Jens Schmidt, Christian Munz, and Jan D. Lunemann
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.159392

Single domain intracellular antibodies from diverse libraries:emphasizing dual functions of LMO2 protein interactions USING A SINGLE VH DOMAIN
Tomoyuki Tanaka, Helen Sewell, Simon Waters, Simon Philips, and Terence H. Rabbitts
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.188193

Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling
Elisabeth Maier, Daniel Hebenstreit, Gernot Posselt, Peter Hammerl, Albert Duschl, and Jutta Horejs-Hoeck
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.144949

Membrane Biology
Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT)
Fernanda Delmondes de Carvalho and Matthias Quick
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.167197

Signal Transduction
Up-regulation of adiponectin by resveratrol: The essential roles of the Akt/FOXO1 and AMPK signaling pathways and DsbA-L
Anping Wang, Meilian Liu, xianling liu, Lily Q. Dong, Randolph D. Glickman, Thomas J. Slaga, Zhiguang Zhou, and Feng Liu
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.188144

Prostaglandin (PG)E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release
Hye Sun Kuehn, Mi-Yeon Jung, Michael A. Beaven, Dean D. Metcalfe, and Alasdair M. Gilfillan
J. Biol. Chem. published 27 October 2010, 10.1074/jbc.M110.164772

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