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:: J. Biol. Chem. JBC Papers in Press for 1 Nov 2010 ::
New Journal of Biological Chemistry JBC Papers in Press articles have been made available
(for the period 31 Oct 2010 to 1 Nov 2010):


Enzymology
Platelet factor 4 inhibits thrombomodulin-dependent activation of thrombin-activatable fibrinolysis inhibitor (TAFI) by thrombin
Laurent O. Mosnier
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.147959
http://www.jbc.org/cgi/content/abstract/M110.147959v1

Thrombin-dependent MMP-2 activity is regulated by heparan sulfate
Bon-Hun Koo, Jung Ho Han, Young Il Yeom, and Doo-Sik Kim
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.171595
http://www.jbc.org/cgi/content/abstract/M110.171595v1


Protein Synthesis and Degradation
Ser120 of Ubc2/Rad6 regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1
Brajesh Kumar, Kimberly G. LeCompte, Jennifer M. Klein, and Arthur L. Haas
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.169136
http://www.jbc.org/cgi/content/abstract/M110.169136v1


Microbiology
Cleavage of the NF-{kappa}B-family protein p65/RelA by the chlamydial protease chlamydial protease-like activity factor (CPAF) impairs pro-inflammatory signalling in cells Infected with chlamydiae
Jan G. Christian, Juliane Vier, Stefan A. Paschen, and Georg Häcker
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.152280
http://www.jbc.org/cgi/content/abstract/M110.152280v1


Molecular Bases of Disease
GRK5 deficiency accelerates β-amyloid accumulation in Tg2576 mice via impaired cholinergic activity
Shaowu Cheng, Longxuan Li, Shuangteng He, Jun Liu, Yuning Sun, Minchao He, Kenneth Grasing, Richard T. Premont, and William Zhiming Suo
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.170894
http://www.jbc.org/cgi/content/abstract/M110.170894v1

A noncompetitive small molecule inhibitor of estrogen-regulated gene expression and breast cancer cell growth that enhances proteasome-dependent degradation of estrogen receptor {alpha}
Nicole M. Patterson, Milu T. Cherian, Chengjian Mao, Irene O. Aninye, Philip D. Reynolds, Rachel Schiff, Paul J. Hergenrother, Steven K. Nordeen, Elizabeth M. Wilson, and David J. Shapiro
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.183723
http://www.jbc.org/cgi/content/abstract/M110.183723v1


Neurobiology
Brain-specific Phgdh deletion reveals a pivotal role for L-serine biosynthesis in controlling the level of D-serine, an NMDA receptor co-agonist, in adult brain
JungHoon Yang, Akira Wada, Kazuyuki Yoshida, Yurika Miyoshi, Tomoko Sayano, Kayoko Esaki, Masami O. Kinoshita, Shozo Tomonaga, Norihiro Azuma, Masahiko Watanabe, Kenji Hamase, Kiyoshi Zaitsu, Takeo Machida, Albee Messing, Shigeyoshi Itohara, Yoshio Hirabayashi, and Shigeki Furuya
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.187443
http://www.jbc.org/cgi/content/abstract/M110.187443v3

Phosphatidylinositol 3-kinase facilitates microtubule-dependent membrane transport for neuronal growth cone guidance
Hiroki Akiyama and Hiroyuki Kamiguchi
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.156489
http://www.jbc.org/cgi/content/abstract/M110.156489v1

PDCD10/CCM3 acts downstream of gamma-protocadherins to regulate neuronal survival
Chengyi Lin, Shuxia Meng, Tina Zhu, and Xiaozhong Wang
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.179895
http://www.jbc.org/cgi/content/abstract/M110.179895v1


Metabolism
Heart-type fatty acid binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance
Laurent Vergnes, Robert Chin, Stephen G. Young, and Karen Reue
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.184754
http://www.jbc.org/cgi/content/abstract/M110.184754v1


Cell Biology
Regulator of G protein signaling 6 (RGS6) induces apoptosis via a mitochondrial-dependent pathway not involving its GTPase-activating protein activity
Biswanath Maity, Jianqi Yang, Jie Huang, Ryan W. Askeland, Soumen Bera, and Rory A. Fisher
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.186700
http://www.jbc.org/cgi/content/abstract/M110.186700v1

The mitochondrial inner membrane GTPase, Optic Atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity
Arezu Jahani-Asl, Karine Pilon-Larose, William Xu, Jason G. MacLaurin, David S. Park, Heidi M. McBride, and Ruth S. Slack
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.167155
http://www.jbc.org/cgi/content/abstract/M110.167155v1

CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network
Jean-Michel Escola, Gabriel Kuenzi, Hubert Gaertner, Michelangelo Foti, and Oliver Hartley
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.153460
http://www.jbc.org/cgi/content/abstract/M110.153460v1

BH3-domains other than Bim and Bid can directly activate BAX/BAK
Han Du, Jacob Wolf, Blanca Schafer, Tudor Moldoveanu, Jerry E. Chipuk, and Tomomi Kuwana
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.167148
http://www.jbc.org/cgi/content/abstract/M110.167148v1

Identification and functional characterization of TMEM16A, a Ca2+-activated Cl- channel activated by extracellular nucleotides, in biliary epithelium
Amal K. Dutta, Al-karim Khimji, Charles Kresge, Abhijit Bugde, Michael Dougherty, Victoria Esser, Yoshiyuki Ueno, Shannon S. Glaser, Gianfranco Alpini, Don C. Rockey, and Andrew P. Feranchak
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.164970
http://www.jbc.org/cgi/content/abstract/M110.164970v1

Regulation of angiogenesis by histone chaperone HIRA-mediated incorporation of lysine 56-Acetylated histone H3.3 at chromatin domains of endothelial genes
Debasree Dutta, Soma Ray, Pratik Home, Biswarup Saha, Shoujian Wang, Nader Sheibani, Ossama Tawfik, Nikki Cheng, and Soumen Paul
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.190025
http://www.jbc.org/cgi/content/abstract/M110.190025v1


Membrane Biology
Acute cholesterol induced anti-natriuretic effects- role of epithelial Na+ channel activity, protein levels and processing
Mouhamed S. Awayda, Karen L. Awayda, Oleh Pochynyuk, Vladislav Bugaj, James D. Stockand, and Rudy M. Ortiz
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.159194
http://www.jbc.org/cgi/content/abstract/M110.159194v1


Signal Transduction
Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion is mediated by the CARMA3-Bcl10-MALT1 signalosome
Phillip C. Delekta, Ingrid J. Apel, Shufang Gu, Katy Siu, Yoshiyuki Hattori, Linda M. McAllister-Lucas, and Peter C. Lucas
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.158949
http://www.jbc.org/cgi/content/abstract/M110.158949v1

Pannexin 1 constitutes the large-conductance cation channel of cardiac myocytes
Marie-Cecile Kienitz, Kirsten Bender, Rolf Dermietzel, Lutz Pott, and Georg Zoidl
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.163477
http://www.jbc.org/cgi/content/abstract/M110.163477v1

Novel function of cardiac protein kinase D as a dynamic regulator of CA2+ sensitivity of contraction
Mariah H. Goodall, Robert D. Wardlow, Rebecca R. Goldblum, Andrew Zinman, W. Jonathan Lederer, William Randall, and Terry B. Rogers
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.179648
http://www.jbc.org/cgi/content/abstract/M110.179648v1

A CSF-1 receptor phosphotyrosine 559 signaling pathway regulates receptor ubiquitination and tyrosine phosphorylation
Ying Xiong, Da Song, Yunfei Cai, Wenfeng Yu, Yee-Guide Yeung, and E. Richard Stanley
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.166702
http://www.jbc.org/cgi/content/abstract/M110.166702v1

Agonist-induced localization of Gq-coupled receptors and GIRK channels to caveolae determines receptor specificity of PIP2 signaling
Shanyu Cui, Won-Kyung Ho, Seong-Tae Kim, and Hana Cho
J. Biol. Chem. published 1 November 2010, 10.1074/jbc.M110.153312
http://www.jbc.org/cgi/content/abstract/M110.153312v1

  
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