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:: Journal of Biological Chemistry ::

 Journal of Biological Chemistry JBC Papers in Press AlertNew Journal of
Biological Chemistry JBC Papers in Press articles have been made available
(for the period 20 May 2012 to 21 May 2012):

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Enzymology
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The PH domain of the Arf exchange factor Brag2 is an allosteric binding
siteXiaoying Jian, James M. Gruschus, Elizabeth Sztul, and Paul A.
RandazzoJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.368084
http://www.jbc.org/cgi/content/abstract/M112.368084v1

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Gene Regulation
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Transcription Factors ER71/ETV2 and SOX9 Participate in a Positive Feedback
Loop in Fetal and Adult Mouse TestisLuciano DiTacchio, Josephine Bowles,
Sook Shin, Dae-Sik Lim, Peter Koopman, and Ralf JanknechtJ. Biol. Chem.
published 21 May 2012, 10.1074/jbc.M111.320101
http://www.jbc.org/cgi/content/abstract/M111.320101v1

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Protein Synthesis and Degradation
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Dissecting mannose 6-phosphate/insulin-like growth factor 2 receptor
complexes that control activation and uptake of plasminogen in cellsVladimir
Leksa, Karin Pfisterer, Gabriela Ondrovicova, Brigitte Binder, Silvia
Lakatosova, Clemens Donner, Herbert B. Schiller, Alexander Zwirzitz,
Katarina Mrvova, Vladimir Pevala, Eva Kutejova, and Hannes StockingerJ.
Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.339663
http://www.jbc.org/cgi/content/abstract/M112.339663v1

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Molecular Bases of Disease
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The Notch pathway attenuates interleukin 1β (IL1β)-mediated
induction of Adenylyl Cyclase 8 (AC8) expression during vascular smooth
muscle cell (VSMC) trans-differentiationZela Keuylian, Jeroen H. F. De
Baaij, Martine Glorian, Clotilde Rouxel, Elise Merlet, Larissa Lipskaia,
Regis Blaise, Veronique Mateo, and Isabelle LimonJ. Biol. Chem. published 21
May 2012, 10.1074/jbc.M111.292516
http://www.jbc.org/cgi/content/abstract/M111.292516v1

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Neurobiology
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-aminobutyric acid type B (GABAB) eeceptor expression is needed for
inhibition of N-type (Cav2.2) calcium channels by analgesic α-
conotoxinsHartmut Cuny, Andrew de Faoite, Thuan G. Huynh, Takahiro Yasuda,
Geza Berecki, and David J. AdamsJ. Biol. Chem. published 21 May 2012,
10.1074/jbc.M112.342998
http://www.jbc.org/cgi/content/abstract/M112.342998v1

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Protein Structure and Folding
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Integrin αIIbβ3 inside-out activation: An in situ conformational
analysis reveals a new mechanismLisa Kurtz, Liyo Kao, Debra Newman, Ira
Kurtz, and Quansheng ZhuJ. Biol. Chem. published 21 May 2012,
10.1074/jbc.M112.360966
http://www.jbc.org/cgi/content/abstract/M112.360966v1

A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei
exhibits cytolytic activitiesLucia Kuhn-Nentwig, Irina M. Fedorova, Benjamin
P. Lüscher, Lukas S. Kopp, Christian Trachsel, Johann Schaller, Xuan
Lan Vu, Thomas Seebeck, Kathrin Streitberger, Wolfgang Nentwig, Erwin Sigel,
and Lev G. MagazanikJ. Biol. Chem. published 21 May 2012,
10.1074/jbc.M112.339051
http://www.jbc.org/cgi/content/abstract/M112.339051v1

Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of
nicotinic acetylcholine receptorYuri N. Utkin, Christoph Weise, Igor E.
Kasheverov, Tatyana V. Andreeva, Elena V. Kryukova, Maxim N. Zhmak,
Vladislav G. Starkov, Anh Hoang Ngoc, Daniel Bertrand, Joachim Ramerstorfer,
Werner Sieghart, Andrew J. Thompson, Sarah C.R. Lummis, and Victor I.
TsetlinJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.363051
http://www.jbc.org/cgi/content/abstract/M112.363051v2

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Cell Biology
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The melanosomal protein PMEL17 as a target for antibody drug conjugate
therapy in melanomaYoujun Chen, Cecile Chalouni, Christine Tan, Robyn Clark,
Rayna Venook, Rachana Ohri, Helga Raab, Ron Firestein, William Mallet, and
Paul PolakisJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.361485
http://www.jbc.org/cgi/content/abstract/M112.361485v1

Melittin modulates keratinocyte function through P2-receptor-dependent ADAM
activationAnselm Sommer, Anja Fries, Isabell Cornelsen, Nancy Speck,
Friedrich Koch-Nolte, Gerald Gimpl, Jörg Andrae, Sucharit Bhakdi, and
Karina ReissJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.362756
http://www.jbc.org/cgi/content/abstract/M112.362756v1

Generation of induced pluripotent stem cells from human renal proximal
tubular cells with only two transcription factors: OCT4 and SOX2Nuria
Montserrat, Maria Jose Ramirez-Bajo, Yun Xia, Ignacio Sancho-Martinez,
Daniel Moya-Rull, Laia Miquel-Serra, Shenglian Yang, Emmanuel Nivet, Carme
Cortina, Federico Gonzalez, Juan Carlos Izpisua Belmonte, and Josep M.
CampistolJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.350413
http://www.jbc.org/cgi/content/abstract/M112.350413v1

Inhibition of mycobacterial infection by the tumor suppressor PTENGuochang
Huang, Gil Redelman Sidi, Neal Rosen, Michael S. Glickman, and Xuejun
JiangJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.351940
http://www.jbc.org/cgi/content/abstract/M112.351940v1

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Developmental Biology
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Calpain induces N-terminal truncation of β-catenin in normal murine
liver development: Diagnostic implications in hepatoblastomasAbigale Lade,
Sarangarajan Ranganathan, Jianhua Luo, and Satdarshan P.S. MongaJ. Biol.
Chem. published 21 May 2012, 10.1074/jbc.M112.378224
http://www.jbc.org/cgi/content/abstract/M112.378224v1

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Immunology
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Heterozygous carriage of a dysfunctional TLR9 allele affects CPG-
oligonucleotide responses in B cellsJelena Knezevic, Dinko Pavlinic, William
A. Rose, Cynthia A. Leifer, Kreso Bendelja, Jelka Gabrilovac, Marijo
Parcina, Gordan Lauc, Andriy V. Kubarenko, Branka Petricevic, Damir Vrbanec,
Ljiljana Bulat-Kardum, Isabelle Bekeredjian-Ding, Jasminka Pavelic, Zlatko
Dembic, and Alexander N. R. WeberJ. Biol. Chem. published 21 May 2012,
10.1074/jbc.M111.337477
http://www.jbc.org/cgi/content/abstract/M111.337477v1

Oxidatively modified LDL inhibits TLR2 and TLR4 responses in human monocytes
but not in macrophagesYashaswini Kannan, Kruthika Sundaram, Chandrakala
Aluganti Narasimhulu, Sampath Parthasarathy, and Mark D. WewersJ. Biol.
Chem. published 21 May 2012, 10.1074/jbc.M111.320960
http://www.jbc.org/cgi/content/abstract/M111.320960v1

Evidence that formation of Vimentin/Mitogen-Activated Protein (MAP) kinase
complex mediates mast cell activation following FcRI/CC chemokine receptor 1
cross-talkMasako Toda, Chuan-Hui Kuo, Satty K. Borman, Ricardo Micheler
Richardson, Akihito Inoko, Masaki Inagaki, Andrea Collins, Klaus Schneider,
and Santa Jeremy OnoJ. Biol. Chem. published 21 May 2012,
10.1074/jbc.M111.319624
http://www.jbc.org/cgi/content/abstract/M111.319624v1

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Membrane Biology
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Cytoskeletal modulation of lipid interactions regulates Lck activityGurunadh
R. Chichili, Robert C. Cail, and William RodgersJ. Biol. Chem. published 21
May 2012, 10.1074/jbc.M111.320747
http://www.jbc.org/cgi/content/abstract/M111.320747v1

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Signal Transduction
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Adrenergic regulation of HCN4 channel requires protein association with beta
2 adrenergic receptorDerek Greene, Seungwoo Kang, Anastasia Kosenko, and
Naoto HoshiJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M112.366955
http://www.jbc.org/cgi/content/abstract/M112.366955v1

Pin1 regulates Smad signaling and pulmonary fibrosisZhong-Jian Shen, Ruedi
K. Braun, Jie Hu, Qifa Xie, Haiyan Chu, Robert B. Love, Levi A. Stodola,
Louis A. Rosenthal, Renee J. Szakaly, Ronald L. Sorkness, and James S.
MalterJ. Biol. Chem. published 21 May 2012, 10.1074/jbc.M111.313684
http://www.jbc.org/cgi/content/abstract/M111.313684v1

Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A
(PP2A) regulatory subunit α4, altering PP2A stability and microtubule-
associated protein phosphorylationGuy R. Watkins, Ning Wang, Matthew D.
Mazalouskas, Rey J. Gomez, Chris R. Guthrie, Brian C. Kraemer, Susann
Schweiger, Benjamin W. Spiller, and Brian E. WadzinskiJ. Biol. Chem.
published 21 May 2012, 10.1074/jbc.M112.368613
http://www.jbc.org/cgi/content/abstract/M112.368613v1


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